a. Client reports of paresthesias have decreased.
b. Client’s blood pressure is stable.
c. Client’s cerebrospinal fluid is clear.
d. Client is free of S&S of thromboembolism.
176. Which characteristic must an antibiotic have in order to be used in the treatment of meningitis?
a. Low protein binding in the bloodstream
b. Ability to cross the blood–brain barrier
c. Effectiveness against gram-negative organisms
d. Resistance to neurotransmitter effects
175. Correct answer: d.
Clients with Guillain–Barré syndrome receive low dose anticoagulation because of the risk for thromboembolism secondary to immobility. Therefore, the desired effect of the treatment is that the client remains free of thromboembolism. This is indicated by absence of the S&S of the disorder. Anticoagulation is not given for paresthesias or unstable blood pressure, neither does it affect the spinal fluid.
176. Correct answer: b.
Antibiotics must be able to cross the blood–brain barrier in order to reach the infective organisms. Not all organisms causing meningitis are gram negative and so this is not a characteristic that must apply to all antibiotics used to treat it. Low protein binding in the blood and resistance to neurotransmitter effects are irrelevant to the ability of an antibiotic to combat meningitis.